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Heparin

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Heparin was first discovered from the liver and was named after the mucopolysulfate sulfate consisting of glucosamine, L-iduronidine, N-acetylglucosamine, and D-glucuronide. The average molecular weight was 15KD, showing strong acidity. It also exists in the lungs, blood vessel walls, intestinal mucosa and other tissues, and is a natural anticoagulant substance in animals. Naturally present in mast cells, it is now mainly extracted from bovine lung or small intestinal mucosa. As an anticoagulant, it is a multimer composed of two polysaccharides alternately linked to each other and has anticoagulant effects in vivo and in vitro. Clinically, it is mainly used for thromboembolic diseases, myocardial infarction, cardiovascular surgery, cardiac catheterization, extracorporeal circulation, and hemodialysis. With the development of pharmacology and clinical medicine, the application of heparin has been expanding.

 

Chinese name: heparin

Chinese alias: heparin sodium heparin

English name: Heparin

English alias: thrombophob;HED heparin;clarin;liquaemin;Enoxaparine;Hepathrom;Lipohepin;Panheparin;Hepsal

CAS number: 9005-49-6

Molecular formula: C26H42N2O37S5 Structural formula:

Molecular weight: 1134.93000 Accurate mass: 1134.01000 PSA: 652.39000

 

9005-49-6

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